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Toxicity of Thimerosal
An Organic Mercurial Added To Vaccines

From The

Toxic Exposure Study Trust (TEST) Foundation

Is this any place to put a toxic organic mercury compound?

Thimerosal is considered the classic lipophilic sulfhydryl reactive agent having been used by scientists for over 30 years to inhibit numerous enzymes and cellular processes (see Thimerosal Studies) virtually all of which are vital for normal cellular functioning (see Thimerosal/sld041.htm).  Moreover, the levels of thimerosal required to produce these many toxic effects were often found to be much lower than the concentrations of thimerosal included in vaccines.  Given these facts, the vaccine manufacturers, the FDA and the CDC must surely have conducted numerous studies on the safety of thimerosal containing vaccines before ever allowing, much less recommending, they be administered to newborns and infants.  If so, where are the results of those studies published?  

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Iatrogenic exposure to mercury after hepatitis B vaccination in pre-term infants.
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 Stajich GV, Lopez GP, Harry SW, Sexson WR. J Pediatr (2000) May; 136(5):679-81 (10802503)

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Thimerosal, a derivative of mercury, is used as a preservative in hepatitis B vaccines. We measured total mercury levels before and after the administration of this vaccine in 15 preterm and 5 term infants. Comparison of pre- and post-vaccination mercury levels showed a significant increase in both preterm and term infants after vaccination. Additionally, post-vaccination mercury levels were significantly higher in preterm infants as compared with term infants. Because mercury is known to be a potential neurotoxin to infants, further study of its pharmacodynamics is warranted.

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Compare this study to the recently published study by Michael E Pichichero, Elsa Cernichiari, Joseph Lopreiato, John Treanor.

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Mercury concentrations and metabolism in infants receiving vaccines containing thiomersal: a descriptive study The Lancet, Volume 360, Number 9347, 30 November 2002.

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Dr. Pichichero's comments on the study: "Removing thimerosal from U.S. vaccines has had several effects, Pichichero says. Since vaccines don't last as long without a preservative, the elimination of thimerosal caused some vaccine makers to produce single-dose vials, which are more expensive to produce, store, and ship. For some vaccines, manufacturers use thimerosal throughout the manufacturing process, then remove the compound, which also adds to the cost of the vaccine. Such actions raised the cost of vaccines, making it less likely that they'll be used as widely as possible."

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After reading the Pichichero et al., study please see Safe Minds Assessment of the Pichichero Thimerosal Study

 

VACCINE QU0TES

 
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''In most vaccine containers, thimerosal is listed as a mercury derivative, a hundredth of a percent. And what I believed, and what everybody else believed, was that it was truly a trace, a biologically insignificant amount. My honest belief is that if the labels had had the mercury content in micrograms, this would have been uncovered years ago. But the fact is, no one did the calculation.''
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By: Neal Halsey M.D., Pediatrician and Vaccinologists, Johns Hopkins University, Chairman of the American Academy of Pediatrics committee on infectious diseases from 1995 through June 1999

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Source: New York Times article, Not-So-Crackpot Autism Theory, by Arthur Allen, November 10, 2002

 
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"The active ingredient in thimerosal is ethylmercury, a close chemical relative of methylmercury. At high doses, methylmercury and some other forms of the heavy metal are known to damage the nervous system. Ethylmercury has not been well-studied, but the amount in vaccines is small. Some children who received the maximum number of thimerosal-containing vaccines on the recommended childhood immunization schedule had exposures to ethylmercury that exceeded some safe exposure guidelines for methylmercury. In addition, some children could be particularly vulnerable or susceptible to mercury exposures because of genetic or other differences."
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By Marie C. McCormick, Professor and Chair, Department of Maternal and Child Health Harvard School of Public Health and Chair, Committee on Immunization Safety Review

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Source: Thimerosal Opening Statement at the Institute of Medicine's Thimerosal-Containing Vaccines and Neurodevelopmental Disorders Meeting held Oct. 1, 2001.

 
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"The important thing to note is that thimerosal is an issue really only for pediatric vaccines for small children. The developing nervous system is very sensitive, so if they're exposed to mercury it's more likely to cause damage."
bulletBy Dr. Pierre Lavigne, director of clinical and medical affairs, Aventis Pasteur
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Source: Flu fighters. Ontario's free mass vaccination program may not be such a good deal after all. Written by Vern Smith.

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Published December 7, 2000 in Eye Weekly http://www.eye.net/eye/issue/issue_12.07.00/news/flu.html or Flu Vaccines

 
bullet"The vaccine experts who added new vaccines into the routine schedule in the late 80’s and early 90’s have acknowledged that they did not add up the cumulative doses of mercury to which our children were exposed.  The CDC ’s own data shows an increased risk of 2.48 for autism in children who received full immunizations by six months compared to a less vaccinated population."
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By Elizabeth Mumper, MD, President and CEO, Advocates for Children, Associate Professor of Clinical Pediatrics, University of Virginia School of Medicine

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Published in an open letter to President Bush In support for a White House Conference on Autism

 

bullet"The idea that vaccines, arguably the top public health achievement of the past half century, are damaging children is such a horrible possibility, or in my eyes a high probability, that no one wants to be associated with it. And that's tragic because it's all been done in the name of good. But it has to be pinned down. It's too important to be just a philosophical debate."
bulletBy Candace Pert MD, Neurologist, Director of Georgetown University's Institute For New Medicine
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Source: Inoculated into oblivion. When families hit the Capitol last week, they demanded answers about the source of their children's autism. Written by By Arthur Allen

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Published April 13, 2000 in Salon.com http://archive.salon.com/health/feature/2000/04/13/shot/index.html and Vaccine Oblivion

 
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"Thimerosal, a mercury preservative, is being phased out of vaccines because of its potential toxicity in vulnerable children and concern from parents and clinicians. Although most of the current evidence favors the safety of the MMR vaccine, especially with the removal of thimerosal, continued research is needed in this area before parents will feel that this issue has been resolved completely."
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By LUCILLE MARCHAND, M.D., B.S.N., University of Wisconsin Medical School,  Madison, Wisconsin

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Source: Autism.  Published in American Family Physician, Nov 1, 2002 http://www.aafp.org/afp/20021101/editorials.html

 
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"On sucking up to special interests: I guess that the back channel passage of that tailor-made -- and White House approved -- amendment to the Homeland Security Bill protecting Eli Lilly, maker of the questionable vaccine preservative Thimerosal, from billions in potential lawsuits just wasn't enough of an insult to democracy. To pour salt in that fresh wound, the administration has asked a federal claims court to block public access to documents unearthed in over a thousand Thimerosal-related lawsuits. Take that, suffering parents of autistic children!"
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By Arianna Huffington

bulletSource: White House Chutzpah, Filed December 12, 2002
bullethttp://www.ariannaonline.com/columns/files/121202.html

WHAT'S NEW

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Homeland Insecurity - US Senate Votes to Keep Vaccine Language in Homeland Security Bill
bulletRep. Dick Armey, R-Texas, says he's behind a provision in the homeland security bill that protects Eli Lilly and Co. (CBS/AP)
bullet"I did it and I'm proud of it," says Armey, R-Texas.

 

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Eli Lilly Shielded from Prosecution Over Damages Caused by Thimerosal

 
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US Government Asks Court to Seal Vaccine Records

 
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Vaccines Are Getting a Booster Shot. As their profit potential jumps, so does new investment in R&D
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Business Week Online, DECEMBER 9, 2002

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By John Carey in Washington, with Kerry Capell in London

 
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Safety of Aluminum Added to Vaccines as a Vaccine Adjuvant
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Dr. Philip Rudnick Ph.D.

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Professor Emeritus, Chemistry

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West Chester University of Pennsylvania

 
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Congressman Dan Burton questions the FDA and CDC officials at thimerosal hearings
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June 19 2002

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A United States congressman is calling for criminal penalties for any government agency that knew about the dangers of Thimerosal in vaccines, and did nothing to protect American children.

 
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Vaccine preservative's effects may have been known
bullet05/21/2002
bulletBy VALERI WILLIAMS / WFAA-TV
bulletDallas/Fort Worth, Channel 8 News
bullethttp://www.wfaa.com/latestnews/stories/wfaa020520_am_vaccine.666583b.html

 

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Mercury in childhood vaccines: what did the government know?
bullet05/22/2002
bulletBy VALERI WILLIAMS / WFAA-TV
bulletDallas/Fort Worth, Channel 8 News
bullethttp://www.wfaa.com/localnews/investigates/stories/wfaa020521_am_vaccine2.b7e9f53.html

 
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FDA's Hypocracy
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By Cindy H. Dubin

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Managing Editor

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Pharmaceutical Formulation and Quality

 
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Eli Lilly Documents Reveal Dangers of Thimerosal
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Press Release from Waters and Kraus LLP

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March 17, 2002

 
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Thimerosal-Containing Vaccines and Neurodevelopmental Outcomes Meeting Agenda
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Held  Monday, July 16, 2001 in Cambridge, MA

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Organized by the the National Academies Institute of Medicine

 
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EXPOSURE TO THIMEROSAL IN VACCINES USED IN CANADIAN INFANT IMMUNIZATION PROGRAMS, WITH RESPECT TO RISK OF NEURODEVELOPMENTAL DISORDERS
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Canada Communicable Disease Report

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Volume 28-09

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1 May 2002

 
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Link found between measles virus and gut abnormalities in children with developmental disorder
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Potential viral pathogenic mechanism for new variant inflammatory bowel disease.

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By Drs. V Uhlmann, C M Martin, O Sheils, L Pilkington, I Silva, A Killalea, S B Murch, A J Wakefield, JJ O'Leary

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Molecular Pathology, April 2002.

 
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Vaccines without thiomersal: why so necessary, why so long coming?
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Dr. A.J. van't Veen

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Department of Dermatology and Venereology, Erasmus University Hospital Rotterdam-Dijkzigt, Rotterdam, The Netherlands.

 
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Press Release from the Law Firm of Waters and Kraus Linking Thimerosal Exposure with Autism.

 
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The Public Health Advisor for the National Immunization Program at the Centers for Disease Control and Prevention Tells Parents that their "Questions regarding thimerosal content or other vaccine constituents should be discussed directly with the product manufacturers for the individual vaccines." 
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E-mail from Dr. Robert Snyder, dated 9/27/01.

 

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Thimerosal-Containing Vaccines and Neurodevelopmental Outcomes Meeting
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Held  Monday, July 16, 2001 in Cambridge, MA

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Organized by the the National Academies Institute of Medicine

 

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In Harm's Way Toxic Threats to Child Development Project

bulletAddresses Toxic Chemical Influences on Developmental Disabilities
bulletIncludes a 140 page, fully referenced, peer reviewed report, addressing the links between toxic chemicals in our environment and learning, behavioral and developmental disabilities in children along with several slide presentations.
bulletAlso available are "Out of Harm's Way" Fact Sheet Series for Health Professionals and Patients PowerPoint Presentation "In Harm's Way Training Program for Health Professionals"

“The number of recommended childhood vaccines has increased substantially over the past several decades. Twenty years ago, children received 7 vaccines routinely and up to 5 shots by 2 years of age. Today, children receive 11 vaccines routinely and as many as 20 shots by age two.” 

Paul A. Offit, M.D., chief of Infectious Diseases and director of the Vaccine Education Center at The Children’s Hospital of Philadelphia 

 

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The ADA Responds to Testimony Given by Dr. Boyd Haley at Hearings Chaired by Representative Dan Burton Regarding the Safety of Mercury in Dental Amalgam

 

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Dr. Boyd Haley responds to the letter from  Robert M. Anderton, D.D.S., J.D., LL.M. challenging his statement to the Committee on Government Reform looking at the topic, Autism-Why the Increased Rates? A One Year Update

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An Assessment of Thimerosal Use in Childhood Vaccines

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By Leslie K. Ball, Robert Ball, and R. Douglas Pratt

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PEDIATRICS Vol. 107 No. 5 May 2001, pp. 1147-1154

 

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Metallothionein  Dysfunction in 99% of Patients Diagnosed with Autism Spectrum Disorders
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By William J. Walsh, Ph.D., biochemist and chief scientist Anjum Usman, M.D., a physician, both of the Pfeiffer Center, Naperville, Illinois

 

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Potential Role of Yeast and Fungi in Autism
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Do Mycotoxins Produced by Pathogenic Yeast and Fungi Contribute to Oral Toxicity and Potentially to Systemic Diseases?

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Published Studies on Mycotoxins Produced by Yeast and Fungi

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Candida-Caused Autism? 

bulletBernard Rimland, Ph.D.
bulletAutism Research Institute

 

TABLE OF CONTENTS

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Thimerosal Toxicity Slide Show

       

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Thimerosal Neurotoxicity
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Part A - In Vitro Treatment of a Neuroblastoma Cell Line with Low Concentrations of Thimerosal Results in Apoptosis

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Part B - In Vitro Treatment of a Neuroblastoma Cell Line with Low Concentrations of Thimerosal Results in Altered Nucleotide Binding

 

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Studies Published in Peer Reviewed Scientific and Medical Journals Demonstrating the Toxicity of Thimerosal

       

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Thimerosal, Vaccines and Autism
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The latest research, reports, press releases, etc. on the possible link between the administration of thimerosal containing vaccines and autism

 

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Thimerosal Content in Some US Licensed Vaccines
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From the Vaccine Safety Institute

 

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Reports on the First and Second International Public Conference on Vaccination
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By Lisa Regan, Mothering Magazine

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Sponsored by the National Vaccine Information Center (NVIC), a child-advocacy organization that promotes vaccine safety and informed choice.

 

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Autistic Disorder
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From the JAMA Patient Page, Vol 285, No. 13, April 4, 2001

 

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Autism: A Unique Type of Mercury Poisoning
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by Sallie Bernard, Albert Enayati, B.S., Ch.E., M.S.M.E., Teresa Binstock, Heidi Roger, Lyn Redwood, R.N., M.S.N., C.R.N.P., Woody McGinnis, M.D.
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ABSTRACT

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INTRODUCTION

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I. SYMPTOM COMPARISON

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II. COMPARISON OF BIOLOGICAL ABNORMALITIES

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III. MECHANISMS, SOURCES & EPIDEMIOLOGY OF EXPOSURE

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IV. DETECTION OF MERCURY IN AUTISTIC CHILDREN

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References

 

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A Letter from Representative Dan Burton, Chairman of the Committee on Government Reform,  to Dr. Donna Shala, Secretary of Health and Human Services, Requesting a   Recall of Thimerosal Containing Vaccines

 

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The American Dental Association Responds to Testimony Given at Representative Burton's Hearings

 

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THE ABCs OF MMRs AND DTPs: IS THERE AN ASSOCIATION BETWEEN VACCINATION AND AUTISM?
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    BY ERIC LONDON: A BIBLIOGRAPHIC ESSAY 

 

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Association of American Physicians and Surgeons (AAPS) Votes to Oppose Vaccine Mandates
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AAPS Resolution Concerning Mandatory Vaccines

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Fact Sheet on Mandatory Vaccines from the AAPS

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Putting Toddlers at Risk with Mandated Vaccines

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By Jane Orient, M.D., Executive director of the American Association of Physicians and Surgeons.

 
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Measles, Mumps, and Rubella - Vaccine Use and Strategies for Elimination of Measles, Rubella, and Congenital Rubella Syndrome and Control of Mumps: Recommendations of the Advisory Committee on Immunization Practices (ACIP).

 
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Thimerosal in Vaccines—An Interim Report to Clinicians from the American Academy of Pediatrics (AAP)

 

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MMR Vaccination and Autism
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By Dr. Andrew J Wakefield, Departments of Medicine and Histopathology, Royal Free and University College Medical School, Hampstead, London NW3 2PF, UK

 

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Autism 99. A National Emergency

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F. Edward Yazbak, MD, FAAP

 

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Autism on the Rise.

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By Laura DeFrancesco

 

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The Verge of Vaccine Mania A Shot for This, a Shot for That. How Much Is Too Much?
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By Nicholas Regush

 

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Vaccinations - Yes or No?
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Attempts at Eradicating Infectious Diseases are Putting Our Children at Risk
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By Dr. Barbara Loe Fisher

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Vaccinations: Modern Lifesavers
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 By Dr. Eugene J. Gangarosa

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Public Health Risks of Not Vaccinating Children
Vol. 285 No. 12, March 28, 2001

                        

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The World Health Organization and Thimerosal in Vaccines

 

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Thimerosal and Gulf War Syndrome
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The Anthrax Vaccine Saga: How Not to Develop a Vaccine Program
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 By Dr. Meryl Nass, M.D.

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Is There A Link Between Receipt Of Multiple Thimerosal Containing Vaccinations, Stress Induced Increases in Blood-Brain Barrier Permeability And Gulf War Syndrome?

    

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Links to Articles, News Releases from Governmental Agencies and Other Websites  Regarding the Safety and Use of Thimerosal

 

 

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Disclaimer

All of the original research shown on this web page was wholly funded by ALT, Inc.   The purpose of this web page is to educate persons in the health care community and the public at large about the potential dangers resulting from exposure to thimerosal containing compounds and substances.  ALT, Inc. does not and has not profited in any way from this research nor does the company offer any goods or services which can be used to detect or monitor for toxicity resulting from exposure to thimerosal.  We at ALT, Inc. believe very strongly in eliminating all unnecessary and avoidable forms of exposure to mercury and mercury containing compounds.  This includes thimerosal in vaccines and mercury in dental "silver" amalgam fillings.  This is especially true of infants, small children, pregnant women and women of child bearing age who are more susceptible to the toxic effects of mercury.   Individuals wishing to express their concerns regarding the use and/or dangers of thimerosal should contact the following individuals:

CDC National Immunization Program

Dr. Walter Orenstein,
Director of the Centers for Disease Control and Prevention's 
National Immunization Program
National Immunization Information Hotline: 1-800-232-2522

Dr. Robert Snyder
E-mail: ros@cdc.gov
Telephone: 404-639-8222

U.S. Food and Drug Administration

Dr. Kathryn Zoon,
Director of the Center for Biologics Evaluation and Research
at the Food and Drug Administration (FDA),

Dr. L. K. Ball
Division of Vaccines and Related Products Applications,
Office of Vaccines Research and Review, Center for Biologics Evaluation and Research,
E-mail: balll@cber.fda.gov

Dr. Gerald Racanow
Telephone: 301-827-2222