Proteins Associated with Senile Plaques

Amyloid b peptide

Complement proteins and inhibitors

Clotting factors Thrombin, tissue plasminogen activator

Apolipoprotein E and lipoprotein receptors

Proteases Cathepsins , trypsin

Protease inhibitors Cystatins, alpha 1-antichymotrypsin, alpha 1-antitrypsin

Growth factors and cytokines bFGF, TGFß, IL-6

Cell adhesion molecules

Proteoglycans

Enzymes AChE, BChE, PKC

Heat shock proteins Adapted from McGreer and McGreer (1995) Brain Res. Rev. 21, 195-218

Previous slide

Next slide

Back to first slide

View graphic version