The Gulf War, Stress And A Leaky Blood-Brain Barrier. Israel Hanin, (1996). Nature Medicine 2:1307-1308.

bullet

“Friedman and colleagues 3 analyzed pyridostigmine’s effects on 35 normal, healthy volunteers during peacetime in a double-blind study.”

bullet

“They report that in the peacetime group documented symptoms were restricted to perturbations of the peripheral nervous system (diarrhea, excess sweating, increased salivation).”

bullet

“By contrast, predominantly central nervous system symptoms were reported by the Israeli soldiers receiving pyridostigmine pretreatment during wartime.”

bullet

“These studies demonstrate a significant correlation between stress and pyridostigmine-induced effects in the central nervous system suggesting that, in troops exposed to emotional stress under conditions of war, the BBB may have unexpectedly become more permeable to administered pyridostigmine.”

bullet

Could the same be true of thimerosal contained in vaccines and toxoids?

3 Friedman et al., (1996). Pyridostigmine brain penetration under
stress enhances neuronal excitability and induces early immediate
transcriptional response. Nature Med. 2:1382-1385.

Previous slide Back to first slide View graphic version