| Thimerosal is a potent inhibitor of several mammalian nucleotide binding proteins vital for normal cellular functioning. |
| Inhibition of nucleotide binding is observed at low micromolar concentrations and is dose dependent. |
| Inhibition of nucleotide binding by thimerosal is not due to the thiosalicylate moiety leaving only the ethyl mercury portion of the molecule as the potential site of toxic interaction. |
| Thimerosal is a more potent inhibitor of ATP binding to purified mammalian proteins than is mercuric (II) cation. |
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